This policy note discusses the main findings of new GSMA research on the relationship between mobile money regulation and usage. The analysis combines data from the Mobile Money Regulatory Index and the Global Findex Database 2017 and covers almost 50,000 individuals across 46 countries. The results are preliminary but show compelling evidence that an enabling regulatory framework is strongly associated with higher mobile money usage. The findings also suggest that an enabling regulatory framework has a stronger association with mobile money usage among women compared to men. This research also contributes to an understanding of the central role that regulation plays in enabling greater access to financial services, especially during the COVID-19 pandemic.